BDBM746040 5-chloro-1-(1-cyclopropyl- 1H-pyrazol-4-yl)-6-{4-[3- methyl(~2~H_4_)oxetan-3- yl]piperazin-1-yl}-1H- indazole::US12319671, Example 4.8

SMILES [2H]C1([2H])OC([2H])([2H])C1(C)N1CCN(c2cc3c(cnn3-c3cnn(C4CC4)c3)cc2Cl)CC1

InChI Key InChIKey=QPKRALQZRMMSSU-RYIWKTDQSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 746040   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM746040(5-chloro-1-(1-cyclopropyl- 1H-pyrazol-4-yl)-6-{4-[...)
Affinity DataIC50: 625nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/25/2025
Entry Details
Go to US Patent