BDBM745525 US20250171467, Compound 23::[S or R]-(6,6-difluoro-1,4- diazabicyclo[3.2.2]nonan-4-yl)-[1- [4-methoxy-3- (trifluoromethyl)phenyl]-1,4,5,6- tetrahydrocyclopenta[c]pyrazol-3- yl]methanone

SMILES COc1ccc(-n2nc(C(=O)N3CC[N@@]4CCC3C(F)(F)C4)c3c2CCC3)cc1C(F)(F)F

InChI Key InChIKey=VOXFKLXKILAZPC-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 745525   

TargetUDP-glucose 6-dehydrogenase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM745525([S or R]-(6,6-difluoro-1,4- diazabicyclo[3.2.2]non...)
Affinity DataEC50:  66nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/23/2025
Entry Details
Go to US Patent