BDBM745361 8-(Benzylsulfonyl)-3-fluoroindolo[2,1-b]quinazoline-6,12-dione ::US20250171452, Compound 33

SMILES O=C1c2cc(S(=O)(=O)Cc3ccccc3)ccc2-n2c1nc1cc(F)ccc1c2=O

InChI Key InChIKey=TXGZJSKQOGNSKC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 745361   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Viscient Bio

US Patent
LigandPNGBDBM745361(8-(Benzylsulfonyl)-3-fluoroindolo[2,1-b]quinazolin...)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/23/2025
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 2(Human)
Viscient Bio

US Patent
LigandPNGBDBM745361(8-(Benzylsulfonyl)-3-fluoroindolo[2,1-b]quinazolin...)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/23/2025
Entry Details
Go to US Patent