BDBM745356 3-Fluoro-6,12-dioxo-6,12-dihydroindolo[2,1-b]quinazoline-8-sulfonamide ::US20250171452, Compound 28

SMILES O=C1c2cc(SCc3ccccc3)ccc2-n2c1nc1cc(F)ccc1c2=O

InChI Key InChIKey=HXNJCVCLQPTFHR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 745356   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Viscient Bio

US Patent
LigandPNGBDBM745356(3-Fluoro-6,12-dioxo-6,12-dihydroindolo[2,1-b]quina...)
Affinity DataIC50: 20nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/23/2025
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 2(Human)
Viscient Bio

US Patent
LigandPNGBDBM745356(3-Fluoro-6,12-dioxo-6,12-dihydroindolo[2,1-b]quina...)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/23/2025
Entry Details
Go to US Patent