BDBM745285 7-methoxy-2- (trans-3-{4- [(piperazin-1- yl)methyl]phenyl} cyclobutyl)[1,2, 4]triazolo[1,5- c]quinazolin-5- amine::US20250171447, Ex-98

SMILES COc1cccc2c1nc(N)n1nc([C@H]3C[C@H](c4ccc(CN5CCNCC5)cn4)C3)nc21

InChI Key InChIKey=RUOHJRLMWPNFCQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 745285   

TargetAdenosine receptor A2a(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM745285(7-methoxy-2- (trans-3-{4- [(piperazin-1- yl)methyl...)
Affinity DataIC50: 1.60nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/23/2025
Entry Details
Go to US Patent