BDBM745278 2-{(1s,3s)-3-[6- (2-amino-1,1- difluoropropan- 2-yl)pyridin-3- yl]cyclobutyl}-7- methoxy[1,2,4] triazolo[1,5- c]quinazolin-5- amine::US20250171447, Ex-91

SMILES COc1cccc2c1nc(N)n1nc([C@H]3C[C@@H](c4ccc(C(C)(N)C(F)F)nc4)C3)nc21

InChI Key InChIKey=KTAUCYRCBGGBKM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 745278   

TargetAdenosine receptor A2a(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM745278(2-{(1s,3s)-3-[6- (2-amino-1,1- difluoropropan- 2-y...)
Affinity DataIC50: 1.10nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/23/2025
Entry Details
Go to US Patent