BDBM745274 2-{3-[5-(2- aminopropan-2- yl)-3- chloropyridin-2- yl]cyclobutyl}-7- methoxy[1,2,4] triazolo[1,5- c]quinazolin-5- amine::US20250171447, Ex-87

SMILES COc1cccc2c1nc(N)n1nc(C3CC(c4ncc(C(C)(C)N)cc4Cl)C3)nc21

InChI Key InChIKey=UFKYQTROIBEYAD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 745274   

TargetAdenosine receptor A2a(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM745274(2-{3-[5-(2- aminopropan-2- yl)-3- chloropyridin-2-...)
Affinity DataIC50: 0.800nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/23/2025
Entry Details
Go to US Patent

TargetAdenosine receptor A2b(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM745274(2-{3-[5-(2- aminopropan-2- yl)-3- chloropyridin-2-...)
Affinity DataIC50: 2.70nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/23/2025
Entry Details
Go to US Patent