BDBM745272 2-{trans-3-[5-(2- aminopropan-2- yl)-3- fluoropyridin-2- yl]cyclobutyl}-7- methoxy [1,2,4] triazolo[1,5- c]quinazolin-5- amine::US20250171447, Ex-85

SMILES COc1cccc2c1nc(N)n1nc([C@H]3C[C@H](c4ncc(C(C)(C)N)cc4F)C3)nc21

InChI Key InChIKey=QOGWDDMRDGPUJD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 745272   

TargetAdenosine receptor A2a(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM745272(2-{trans-3-[5-(2- aminopropan-2- yl)-3- fluoropyri...)
Affinity DataIC50: 2.70nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/23/2025
Entry Details
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TargetAdenosine receptor A2b(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM745272(2-{trans-3-[5-(2- aminopropan-2- yl)-3- fluoropyri...)
Affinity DataIC50: 1.30nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/23/2025
Entry Details
Go to US Patent