BDBM745265 2-(cis-3-{5- [(1S)-1-amino- 2,2,2- trifluoroethyl] pyridin-2-yl} cyclobutyl)-7- methoxy[1,2,4] triazolo[1,5-c] quinazolin-5-amine::US20250171447, Ex-78

SMILES COc1cccc2c1nc(N)n1nc([C@H]3C[C@@H](c4ccc([C@H](N)C(F)(F)F)cn4)C3)nc21

InChI Key InChIKey=QLTXOPJPGJLXGW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 745265   

TargetAdenosine receptor A2a(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM745265(2-(cis-3-{5- [(1S)-1-amino- 2,2,2- trifluoroethyl]...)
Affinity DataIC50: 1.90nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/23/2025
Entry Details
Go to US Patent