BDBM745250 2-{6-[cis-3-(5-amino- 7,9- difluoro[1,2,4]triazolo [1,5-c]quinazolin-2- yl)cyclobutyl]pyridin- 3-yl} propan-2-ol::US20250171447, Ex-63

SMILES CC(C)(O)c1ccc([C@H]2C[C@@H](c3nc4c5cc(F)cc(F)c5nc(N)n4n3)C2)nc1

InChI Key InChIKey=PNERTGZTEYKOIH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 745250   

TargetAdenosine receptor A2a(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM745250(2-{6-[cis-3-(5-amino- 7,9- difluoro[1,2,4]triazolo...)
Ligand Info
In Depth
Date in BDB:
9/23/2025
Entry Details
Go to US Patent

TargetAdenosine receptor A2b(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM745250(2-{6-[cis-3-(5-amino- 7,9- difluoro[1,2,4]triazolo...)
Affinity DataIC50: 0.400nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/23/2025
Entry Details
Go to US Patent