BDBM745233 2-{6-[cis-3-(5-amino- 9-fluoro-7- methoxy [1,2,4]triazolo [1,5-c]quinazolin-2- yl)cyclobutyl]pyridin- 3-yl} propan-2-ol::US20250171447, Ex-45

SMILES COc1cc(F)cc2c1nc(N)n1nc([C@H]3C[C@@H](c4ccc(C(C)(C)O)cn4)C3)nc21

InChI Key InChIKey=JOOZZINVJGGWGX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 745233   

TargetAdenosine receptor A2a(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM745233(2-{6-[cis-3-(5-amino- 9-fluoro-7- methoxy [1,2,4]t...)
Affinity DataIC50: 1.60nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/23/2025
Entry Details
Go to US Patent

TargetAdenosine receptor A2b(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM745233(2-{6-[cis-3-(5-amino- 9-fluoro-7- methoxy [1,2,4]t...)
Affinity DataIC50: 6.20nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/23/2025
Entry Details
Go to US Patent