BDBM745227 9-fluoro-2-[2-fluoro-2- phenylcyclopropyl]-7- methoxy[1,2,4]triazolo [1,5-c]quinazolin- 5-amine::US20250171447, Ex-39

SMILES COc1cc(F)cc2c1nc(N)n1nc(C3CC3(F)c3ccccc3)nc21

InChI Key InChIKey=BRZROTDFYDYGHG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 745227   

TargetAdenosine receptor A2a(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM745227(9-fluoro-2-[2-fluoro-2- phenylcyclopropyl]-7- meth...)
Affinity DataIC50: 0.600nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/23/2025
Entry Details
Go to US Patent

TargetAdenosine receptor A2b(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM745227(9-fluoro-2-[2-fluoro-2- phenylcyclopropyl]-7- meth...)
Affinity DataIC50: 71.9nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/23/2025
Entry Details
Go to US Patent