BDBM745194 6-[2-(5-amino-7- methoxy[1,2,4]triazolo [1,5-c]quinazolin-2-yl)cyclopropyl]-2,3-dihydro-1H-isoindol- 1-one::US20250171447, Ex-6

SMILES COc1cccc2c1nc(N)n1nc(C3CC3c3ccc4c(c3)C(=O)NC4)nc21

InChI Key InChIKey=WALSUWKFABRSAG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 745194   

TargetAdenosine receptor A2a(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM745194(6-[2-(5-amino-7- methoxy[1,2,4]triazolo [1,5-c]qui...)
Affinity DataIC50: 0.900nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/23/2025
Entry Details
Go to US Patent

TargetAdenosine receptor A2b(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM745194(6-[2-(5-amino-7- methoxy[1,2,4]triazolo [1,5-c]qui...)
Affinity DataIC50: 13.2nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/23/2025
Entry Details
Go to US Patent