BDBM744772 4-(7,8-dihydro-5H-6-oxa-1- azanaphth-3-ylamino)-2-[3- methoxy-4-(3- piperidinopropoxy)phenylamino] pyrimidine::US20250171431, Compound 53

SMILES COc1cc(Nc2nccc(Nc3cnc4c(c3)COCC4)n2)ccc1OCCCN1CCCCC1

InChI Key InChIKey=RYMHWBAJQIMTGF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 744772   

TargetInsulin-like growth factor 1 receptor(Human)
Horizon Therapeutics Ireland Dac

US Patent
LigandPNGBDBM744772(4-(7,8-dihydro-5H-6-oxa-1- azanaphth-3-ylamino)-2-...)
Affinity DataIC50: 500nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/23/2025
Entry Details
Go to US Patent