BDBM744769 4-(6,7-difluoro-3-quinolylamino)- 2-{5-methoxy-6-(2-oxa-6-aza-6-spiro[3.3]heptyl)-3-pyridylamino}pyrimidine::US20250171431, Compound 50

SMILES COc1cc(Nc2nccc(Nc3cnc4cc(F)c(F)cc4c3)n2)cnc1N1CC2(COC2)C1

InChI Key InChIKey=SJHXPWQZZLPYFX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 744769   

TargetInsulin-like growth factor 1 receptor(Human)
Horizon Therapeutics Ireland Dac

US Patent
LigandPNGBDBM744769(4-(6,7-difluoro-3-quinolylamino)- 2-{5-methoxy-6-(...)
Affinity DataIC50: 500nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/23/2025
Entry Details
Go to US Patent