BDBM744762 5-[4-(2,3-dihydro-1,4-dioxa- 5-aza-7-naphthylamino)-2- pyrimidinylamino]-2-[(1s,3s)- 3- (dimethylamino)cyclobutoxy] benzonitrile::US20250171431, Compound 43

SMILES CN(C)[C@H]1C[C@@H](Oc2ccc(Nc3nccc(Nc4cnc5c(c4)OCCO5)n3)cc2C#N)C1

InChI Key InChIKey=IZFVYWMEMZXPDV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 744762   

TargetInsulin-like growth factor 1 receptor(Human)
Horizon Therapeutics Ireland Dac

US Patent
LigandPNGBDBM744762(5-[4-(2,3-dihydro-1,4-dioxa- 5-aza-7-naphthylamino...)
Affinity DataIC50: 500nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/23/2025
Entry Details
Go to US Patent