BDBM744757 4-(3-quinolylamino)-2-{p- [(1s, 4s)-4- morpholinocyclohexyloxy] phenylamino}pyrimidine::US20250171431, Compound 39

SMILES c1ccc2ncc(Nc3ccnc(Nc4ccc(O[C@H]5CC[C@@H](N6CCOCC6)CC5)cc4)n3)cc2c1

InChI Key InChIKey=BDTZWUVNRADLOY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 744757   

TargetInsulin-like growth factor 1 receptor(Human)
Horizon Therapeutics Ireland Dac

US Patent
LigandPNGBDBM744757(4-(3-quinolylamino)-2-{p- [(1s, 4s)-4- morpholinoc...)
Affinity DataIC50: 500nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/23/2025
Entry Details
Go to US Patent