BDBM744734 2-{3-methoxy-4-[(1s,4s)-4- morpholinocyclohexyloxy] phenylamino}-4-(3- quinolylamino)pyrimidine::US20250171431, Compound 18

SMILES COc1cc(Nc2nccc(Nc3cnc4ccccc4c3)n2)ccc1O[C@H]1CC[C@@H](N2CCOCC2)CC1

InChI Key InChIKey=WTQJJZXSHLJOSQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 744734   

TargetInsulin-like growth factor 1 receptor(Human)
Horizon Therapeutics Ireland Dac

US Patent
LigandPNGBDBM744734(2-{3-methoxy-4-[(1s,4s)-4- morpholinocyclohexyloxy...)
Affinity DataIC50: 500nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/23/2025
Entry Details
Go to US Patent