BDBM744651 (5S)-5-methyl-6-{3-(trifluoromethyl)-4-[3-(trifluoromethyl)-1H-pyrazol-1-yl]phenyl}-4,5-dihydro-1,2,4-triazin-3(2H)-one::US20250170136, Example 1

SMILES C[C@@H]1NC(=O)NN=C1c1ccc(-n2ccc(C(F)(F)F)n2)c(C(F)(F)F)c1

InChI Key InChIKey=HXWHIRFDKPRPBR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 744651   

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Human)
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US Patent
LigandPNGBDBM744651((5S)-5-methyl-6-{3-(trifluoromethyl)-4-[3-(trifluo...)
Affinity DataIC50: 91nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/23/2025
Entry Details
Go to US Patent

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM744651((5S)-5-methyl-6-{3-(trifluoromethyl)-4-[3-(trifluo...)
Affinity DataIC50: 81nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/23/2025
Entry Details
Go to US Patent