BDBM744035 N-(4-((1-Isopropyl-1H-[1,2,3]triazolo[4,5- h]quinazolin-8-yl)amino)phenyl)-N-(2- morpholinoethyl)methanesulfonamide::US12312355, Compound I-37

SMILES CC(C)n1nnc2ccc3cnc(Nc4ccc(N(CCN5CCOCC5)S(C)(=O)=O)cc4)nc3c21

InChI Key InChIKey=NBAYTRKTRZCILV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 744035   

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Human)
Chengdu Cynogen Bio-Pharmaceutical Technology

US Patent
LigandPNGBDBM744035(N-(4-((1-Isopropyl-1H-[1,2,3]triazolo[4,5- h]quina...)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/21/2025
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Human)
Chengdu Cynogen Bio-Pharmaceutical Technology

US Patent
LigandPNGBDBM744035(N-(4-((1-Isopropyl-1H-[1,2,3]triazolo[4,5- h]quina...)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/21/2025
Entry Details
Go to US Patent

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Chengdu Cynogen Bio-Pharmaceutical Technology

US Patent
LigandPNGBDBM744035(N-(4-((1-Isopropyl-1H-[1,2,3]triazolo[4,5- h]quina...)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/21/2025
Entry Details
Go to US Patent