BDBM744026 N-(2-Fluoro-4-(piperazin-1-yl)phenyl)- 1-isopropyl-1H-[1,2,3]triazolo[4,5-h]quin- azolin-8-amine hydrochloride::US12312355, Compound I-28

SMILES CC(C)n1nnc2ccc3cnc(Nc4ccc(N5CCNCC5)cc4F)nc3c21

InChI Key InChIKey=CUMXTFLWEIPWGO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 744026   

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Human)
Chengdu Cynogen Bio-Pharmaceutical Technology

US Patent
LigandPNGBDBM744026(N-(2-Fluoro-4-(piperazin-1-yl)phenyl)- 1-isopropyl...)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/21/2025
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Human)
Chengdu Cynogen Bio-Pharmaceutical Technology

US Patent
LigandPNGBDBM744026(N-(2-Fluoro-4-(piperazin-1-yl)phenyl)- 1-isopropyl...)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/21/2025
Entry Details
Go to US Patent

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Chengdu Cynogen Bio-Pharmaceutical Technology

US Patent
LigandPNGBDBM744026(N-(2-Fluoro-4-(piperazin-1-yl)phenyl)- 1-isopropyl...)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/21/2025
Entry Details
Go to US Patent