BDBM744023 N-(4-(4-Ethylpiperazin-1-yl)phenyl)-1-iso- propyl-1H-[1,2,3]triazolo[4,5-h]quin- azolin-8-amine::US12312355, Compound I-25

SMILES CCN1CCN(c2ccc(Nc3ncc4ccc5nnn(C(C)C)c5c4n3)cc2)CC1

InChI Key InChIKey=KERNLPZPNFNVHO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 744023   

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Human)
Chengdu Cynogen Bio-Pharmaceutical Technology

US Patent
LigandPNGBDBM744023(N-(4-(4-Ethylpiperazin-1-yl)phenyl)-1-iso- propyl-...)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/21/2025
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Human)
Chengdu Cynogen Bio-Pharmaceutical Technology

US Patent
LigandPNGBDBM744023(N-(4-(4-Ethylpiperazin-1-yl)phenyl)-1-iso- propyl-...)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/21/2025
Entry Details
Go to US Patent

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Chengdu Cynogen Bio-Pharmaceutical Technology

US Patent
LigandPNGBDBM744023(N-(4-(4-Ethylpiperazin-1-yl)phenyl)-1-iso- propyl-...)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/21/2025
Entry Details
Go to US Patent