BDBM744020 1-Cyclopentyl-N-(5-(piperazin-1-yl)pyridin- 2-yl)-1H-[1,2,3]triazolo[4,5-h]quinazolin- 8-amine hydrochloride::US12312355, Compound I-22

SMILES c1cc(Nc2ncc3ccc4nnn(C5CCCC5)c4c3n2)ncc1N1CCNCC1

InChI Key InChIKey=XKRIDUMADLJRQK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 744020   

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Human)
Chengdu Cynogen Bio-Pharmaceutical Technology

US Patent
LigandPNGBDBM744020(1-Cyclopentyl-N-(5-(piperazin-1-yl)pyridin- 2-yl)-...)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/21/2025
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Human)
Chengdu Cynogen Bio-Pharmaceutical Technology

US Patent
LigandPNGBDBM744020(1-Cyclopentyl-N-(5-(piperazin-1-yl)pyridin- 2-yl)-...)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/21/2025
Entry Details
Go to US Patent