BDBM743994 US12312329, Example T-2

SMILES C=CC(=O)Nc1cc(Nc2ncc(F)c(-n3cc(CN(C)C)c(-c4ccccc4)n3)n2)c(OC)nc1N1CCOCC1

InChI Key InChIKey=VOMZDVUUWNOUPS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 743994   

TargetEpidermal growth factor receptor(Human)
Shenzhen Targetrx

US Patent
LigandPNGBDBM743994(US12312329, Example T-2)
Affinity DataIC50: 3.33nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/21/2025
Entry Details
Go to US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Shenzhen Targetrx

US Patent
LigandPNGBDBM743994(US12312329, Example T-2)
Affinity DataIC50: 0.440nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/21/2025
Entry Details
Go to US Patent