BDBM743993 US12312329, Example T-1

SMILES C=CC(=O)NC1=CC(Nc2nccc(N3CC(CN(C)C)C(c4ccccc4)=N3)n2)C(OC)N=C1N1CCOCC1

InChI Key InChIKey=UZNLYSOTLMPTED-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 743993   

TargetEpidermal growth factor receptor(Human)
Shenzhen Targetrx

US Patent
LigandPNGBDBM743993(US12312329, Example T-1)
Affinity DataIC50: 1.29nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/21/2025
Entry Details
Go to US Patent

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Shenzhen Targetrx

US Patent
LigandPNGBDBM743993(US12312329, Example T-1)
Affinity DataIC50: 0.400nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/21/2025
Entry Details
Go to US Patent