BDBM743782 2-{[6-({5-chloro-2-[4- ({1-[2-(2,6- dioxopiperidin-3-yl)-1,3- dioxo-2,3-dihydro-1H- isoindol-5-yl]piperidin-4- yl}methyl)piperazin-1- yl]pyrimidin-4- yl}amino)-1-cyclopropyl- 2-oxo-1,2- dihydroquinolin-3- yl]oxy}-N- methylacetamide::US12310975, Example 323

SMILES CNC(=O)COc1cc2cc(Nc3nc(N4CCN(CC5CCN(c6ccc7c(c6)C(=O)N(C6CCC(=O)NC6=O)C7=O)CC5)CC4)ncc3Cl)ccc2n(C2CC2)c1=O

InChI Key InChIKey=XTQJJGXSMYTCBR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 743782   

TargetB-cell lymphoma 6 protein(Human)
Arvinas Operations

US Patent
LigandPNGBDBM743782(2-{[6-({5-chloro-2-[4- ({1-[2-(2,6- dioxopiperidin...)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/21/2025
Entry Details
Go to US Patent