BDBM743769 2-{[6-({5-chloro-2-[4- ({1-[2-(2,6- dioxopiperidin-3-yl)-1,3- dioxo-2,3-dihydro-1H- isoindol-4-yl]piperidin-4- yl}methyl)piperazin-1- yl]pyrimidin-4- yl}amino)-1-ethyl-2-oxo- 1,2-dihydroquinolin-3- yl]oxy}-N- methylacetamide::US12310975, Example 310

SMILES CCn1c(=O)c(OCC(=O)NC)cc2cc(Nc3nc(N4CCN(CC5CCN(c6cccc7c6C(=O)N(C6CCC(=O)NC6=O)C7=O)CC5)CC4)ncc3Cl)ccc21

InChI Key InChIKey=RFMJERLFWWZBKX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 743769   

TargetB-cell lymphoma 6 protein(Human)
Arvinas Operations

US Patent
LigandPNGBDBM743769(2-{[6-({5-chloro-2-[4- ({1-[2-(2,6- dioxopiperidin...)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/21/2025
Entry Details
Go to US Patent