BDBM743710 2-((6-((5-chloro-2-(4-((4- (2-(2,6-dioxopiperidin-3- yl)-1,3-dioxoisoindolin-5- yl)piperazin-1- yl)methyl)-4- hydroxypiperidin-1- yl)pyrimidin-4- yl)amino)-1-methyl-2- oxo-1,2-dihydroquinolin- 3-yl)oxy)-N- methylacetamide::US12310975, Example 245

SMILES CNC(=O)COc1cc2cc(Nc3nc(N4CCC(O)(CN5CCN(c6ccc7c(c6)C(=O)C(C6CCC(=O)NC6=O)C7=O)CC5)CC4)ncc3Cl)ccc2n(C)c1=O

InChI Key InChIKey=RYJMSRAFAYCCMJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 743710   

TargetB-cell lymphoma 6 protein(Human)
Arvinas Operations

US Patent
LigandPNGBDBM743710(2-((6-((5-chloro-2-(4-((4- (2-(2,6-dioxopiperidin-...)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/21/2025
Entry Details
Go to US Patent