BDBM743620 3-(5-(4-(3-(4-(5-chloro-4- ((1-methyl-2-oxo-3-(2- oxopropoxy)-1,2- dihydroquinolin-6- yl)amino)pyrimidin-2- yl)piperazin-1- yl)propyl)piperazin-1-yl)- 1-oxoisoindolin-2- yl)piperidine-2,6-dione::US12310975, Example 137

SMILES CC(=O)COc1cc2cc(Nc3nc(N4CCN(CCCN5CCN(c6ccc7c(c6)CN(C6CCC(=O)NC6=O)C7=O)CC5)CC4)ncc3Cl)ccc2n(C)c1=O

InChI Key InChIKey=CDUZANRATWUHMR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 743620   

TargetB-cell lymphoma 6 protein(Human)
Arvinas Operations

US Patent
LigandPNGBDBM743620(3-(5-(4-(3-(4-(5-chloro-4- ((1-methyl-2-oxo-3-(2- ...)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/21/2025
Entry Details
Go to US Patent