BDBM743202 US20250163064, Example 61

SMILES C=Cc1cc2c(N3CCOCC(C)(O)C3)nc(OC[C@@]34CCCN3C[C@H](F)C4)nc2c(F)c1-c1ccc(F)c2sc(N)c(C#N)c12

InChI Key InChIKey=GJRKVDBUKDWBRM-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 743202   

Targetkras g12d tr-fret(Human)
Amgen

US Patent

LigandBDBM743202(US20250163064, Example 61)Copy SMILESCopy InChI

Affinity DataIC50: 5nMMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand Info

In Depth
Date in BDB:
9/19/2025
Entry Details
Copy Entry DOIGo to US Patent

Copy Rxn URL

Targetkras g12d coupled exchange(Human)
Amgen

US Patent

LigandBDBM743202(US20250163064, Example 61)Copy SMILESCopy InChI

Affinity DataIC50: 3nMMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand Info

In Depth
Date in BDB:
9/19/2025
Entry Details
Copy Entry DOIGo to US Patent

Copy Rxn URL