BDBM743200 2-Amino-4-(6- chloro-8-fluoro- 4-(6-fluoro-1,4- oxazepan-4-yl)- 2-(((2R,7aS)-2- fluorotetrahydro- 1H-pyrrolizin- 7a(5H)- yl)methoxy) quinazolin-7-yl)-7- fluorobenzo[b] thiophene-3- carbonitrile Isomer 2::US20250163064, Example 59

SMILES N#Cc1c(N)sc2c(F)ccc(-c3c(Cl)cc4c(N5CCOCC(F)C5)nc(OC[C@@]56CCCN5C[C@H](F)C6)nc4c3F)c12

InChI Key InChIKey=GHGDXGIBYAFMJZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 743200   

Targetkras g12d tr-fret(Human)
Amgen

US Patent
LigandPNGBDBM743200(2-Amino-4-(6- chloro-8-fluoro- 4-(6-fluoro-1,4- ox...)
Ligand Info
In Depth
Date in BDB:
9/19/2025
Entry Details
Go to US Patent

Targetkras g12d coupled exchange(Human)
Amgen

US Patent
LigandPNGBDBM743200(2-Amino-4-(6- chloro-8-fluoro- 4-(6-fluoro-1,4- ox...)
Ligand Info
In Depth
Date in BDB:
9/19/2025
Entry Details
Go to US Patent