BDBM742458 4-methyl-1-[3-(4-prop- 2-enoylpiperazin-1- yl)propyl]-5- [[2-[6-(2,2,2- trifluoroethyl) quinazolin-4-yl]-2,7- diazaspiro[3.5]nonan- 7-yl]methyl]indole-2- carbonitrile::US20250163061, Compound 66

SMILES C=CC(=O)N1CCN(CCCn2c(C#N)cc3c(C)c(CN4CCC5(CC4)CN(c4ncnc6ccc(CC(F)(F)F)cc46)C5)ccc32)CC1

InChI Key InChIKey=FJTWREHSUNTLTD-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 742458   

TargetMenin(Human)
Bala Therapeutics

US Patent
LigandPNGBDBM742458(4-methyl-1-[3-(4-prop- 2-enoylpiperazin-1- yl)prop...)
Affinity DataEC50: <75nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/19/2025
Entry Details
Go to US Patent