BDBM741059 S-(2-((5-((6-carbamoyl-4-(3-chloro-4-(3-cyclopropylurea)phenoxy)quinolin-7-yl)oxy)pentyl)amino)-2-oxo-ethyl)thioacetate::US12304898, Example 69

SMILES CC(=O)SCC(=O)NCCCCCOc1cc2nccc(Oc3ccc(NC(=O)NC4CC4)c(Cl)c3)c2cc1C(N)=O

InChI Key InChIKey=HWSPZCPLTSAAED-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 741059   

TargetHistone deacetylase 6(Human)
Primegene (Beijing)

US Patent
LigandPNGBDBM741059(S-(2-((5-((6-carbamoyl-4-(3-chloro-4-(3-cyclopropy...)
Affinity DataIC50: 8.94nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/19/2025
Entry Details
Go to US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Primegene (Beijing)

US Patent
LigandPNGBDBM741059(S-(2-((5-((6-carbamoyl-4-(3-chloro-4-(3-cyclopropy...)
Affinity DataIC50: 0.960nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/19/2025
Entry Details
Go to US Patent