BDBM741053 S-(2-((5-((4-(2-fluoro-4-(1-((4-fluorophenyl)carbamoyl)cyclopropane-1-carboxamido)phenoxy)-6-methoxyquinolin-7-yl)oxy)pentyl)amino)-2-oxo-ethyl)thioacetate::US12304898, Example 57

SMILES COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCCCNC(=O)CSC(C)=O

InChI Key InChIKey=YHJJMTBIDJGJLC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 741053   

TargetHistone deacetylase 6(Human)
Primegene (Beijing)

US Patent
LigandPNGBDBM741053(S-(2-((5-((4-(2-fluoro-4-(1-((4-fluorophenyl)carba...)
Affinity DataIC50: 48.3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/19/2025
Entry Details
Go to US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Primegene (Beijing)

US Patent
LigandPNGBDBM741053(S-(2-((5-((4-(2-fluoro-4-(1-((4-fluorophenyl)carba...)
Affinity DataIC50: 20nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/19/2025
Entry Details
Go to US Patent