BDBM741049 (E)-N-(3-fluoro-4-((7-((7-mercaptoheptyl-2-en-1-yl)oxy)-6-methoxyquinolin-4-yl)oxy)phenyl)-N-(4-fluorophenyl)cyclopropane-1,1-diformamide::US12304898, Example 25

SMILES COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OC/C=C/CCCCS

InChI Key InChIKey=FXEYTEVFAXADJU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 741049   

TargetHistone deacetylase 6(Human)
Primegene (Beijing)

US Patent
LigandPNGBDBM741049((E)-N-(3-fluoro-4-((7-((7-mercaptoheptyl-2-en-1-yl...)
Affinity DataIC50: 34.8nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/19/2025
Entry Details
Go to US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Primegene (Beijing)

US Patent
LigandPNGBDBM741049((E)-N-(3-fluoro-4-((7-((7-mercaptoheptyl-2-en-1-yl...)
Affinity DataIC50: 79nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/19/2025
Entry Details
Go to US Patent