BDBM740765 Preparation of 6-(6-(methylsulfinyl)pyridin-2-yl)-N2,N4-bis((R)-1,1,1-trifluoropropan-2-yl)-1,3,5-triazine-2,4-diamine ::US12303512, Compound 2

SMILES C[C@@H](Nc1nc(N[C@H](C)C(F)(F)F)nc(-c2cccc(S(C)=O)n2)n1)C(F)(F)F

InChI Key InChIKey=IESPVJDCWDMFAC-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 740765   

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Servier Pharmaceuticals

US Patent
LigandPNGBDBM740765(Preparation of 6-(6-(methylsulfinyl)pyridin-2-yl)-...)
Affinity DataIC50: 4.88E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/19/2025
Entry Details
Go to US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Servier Pharmaceuticals

US Patent
LigandPNGBDBM740765(Preparation of 6-(6-(methylsulfinyl)pyridin-2-yl)-...)
Affinity DataIC50: 161nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/19/2025
Entry Details
Go to US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Human)
Servier Pharmaceuticals

US Patent
LigandPNGBDBM740765(Preparation of 6-(6-(methylsulfinyl)pyridin-2-yl)-...)
Affinity DataIC50: 451nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/19/2025
Entry Details
Go to US Patent

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Human)
Servier Pharmaceuticals

US Patent
LigandPNGBDBM740765(Preparation of 6-(6-(methylsulfinyl)pyridin-2-yl)-...)
Affinity DataIC50: 1.00E+5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/19/2025
Entry Details
Go to US Patent

TargetIsocitrate dehydrogenase [NADP], mitochondrial(Human)
Servier Pharmaceuticals

US Patent
LigandPNGBDBM740765(Preparation of 6-(6-(methylsulfinyl)pyridin-2-yl)-...)
Affinity DataIC50: 1.20E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/19/2025
Entry Details
Go to US Patent

TargetIsocitrate dehydrogenase [NADP], mitochondrial(Human)
Servier Pharmaceuticals

US Patent
LigandPNGBDBM740765(Preparation of 6-(6-(methylsulfinyl)pyridin-2-yl)-...)
Affinity DataIC50: 209nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/19/2025
Entry Details
Go to US Patent

TargetIsocitrate dehydrogenase [NADP], mitochondrial [R140Q](Human)
Servier Pharmaceuticals

US Patent
LigandPNGBDBM740765(Preparation of 6-(6-(methylsulfinyl)pyridin-2-yl)-...)
Affinity DataIC50: 552nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/19/2025
Entry Details
Go to US Patent

TargetIsocitrate dehydrogenase [NADP], mitochondrial [R140Q](Human)
Servier Pharmaceuticals

US Patent
LigandPNGBDBM740765(Preparation of 6-(6-(methylsulfinyl)pyridin-2-yl)-...)
Affinity DataIC50: 146nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/19/2025
Entry Details
Go to US Patent