BDBM740597 3-(1-acetyl-3-piperidyl)-1,8-dimethyl-5- [[(1R)-1-[3- (trifluoromethyl)phenyl]ethyl]amino] pyrido[2,3-d]pyridazin-2-one::US20250154147, Example 18

SMILES CC(=O)N4CCCC(c3cc2c(N[C@H](C)c1cccc(C(F)(F)F)c1)nnc(C)c2n(C)c3=O)C4

InChI Key InChIKey=QCUMTTYNYIOUFG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 740597   

TargetGTPase KRas/Son of sevenless homolog 1 [564-1049](Human)
Jazz Pharmaceuticals Ireland

US Patent
LigandPNGBDBM740597(3-(1-acetyl-3-piperidyl)-1,8-dimethyl-5- [[(1R)-1-...)
Affinity DataIC50: 43.7nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/16/2025
Entry Details
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