BDBM740590 3-(cyclopenten-1-yl)-5-[[(1R)-1-[3- (difluoromethyl)phenyl]ethyl]amino]-1,8- dimethyl-pyrido[2,3-d]pyridazin-2-one::US20250154147, Example 11

SMILES Cc1nnc(N[C@H](C)c2cccc(CC(F)F)c2)c2cc(C3=CCCC3)c(=O)n(C)c12

InChI Key InChIKey=MLLOQMWVUKWXHG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 740590   

TargetGTPase KRas/Son of sevenless homolog 1 [564-1049](Human)
Jazz Pharmaceuticals Ireland

US Patent
LigandPNGBDBM740590(3-(cyclopenten-1-yl)-5-[[(1R)-1-[3- (difluoromethy...)
Affinity DataIC50: 178nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/16/2025
Entry Details
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