BDBM740585 1-methyl-6-[(3-methyloxetan-3- yl)methyl]-4-[[(1R)-1-[3- (trifluoromethyl)phenyl]ethyl]amino] pyrido[3,4-d]pyridazin-7-one::US20250154147, Example 6

SMILES Cc3nnc(N[C@H](C)c1cccc(C(F)(F)F)c1)c4cn(CC2(C)COC2)c(=O)cc34

InChI Key InChIKey=BAJHOMCOJCYAIK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 740585   

TargetGTPase KRas/Son of sevenless homolog 1 [564-1049](Human)
Jazz Pharmaceuticals Ireland

US Patent
LigandPNGBDBM740585(1-methyl-6-[(3-methyloxetan-3- yl)methyl]-4-[[(1R)...)
Affinity DataIC50: 457nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/16/2025
Entry Details
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