BDBM740580 6-cyclopentyl-1-methyl-4-[1-[3- (trifluoromethyl)phenyl]ethylamino] pyrido[3,4-d]pyridazin-7-one::US20250154147, Example 1

SMILES Cc3nnc(NC(C)c1cccc(C(F)(F)F)c1)c4cn(C2CCCC2)c(=O)cc34

InChI Key InChIKey=XXNKDNLZTFCGPF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 740580   

TargetGTPase KRas/Son of sevenless homolog 1 [564-1049](Human)
Jazz Pharmaceuticals Ireland

US Patent
LigandPNGBDBM740580(6-cyclopentyl-1-methyl-4-[1-[3- (trifluoromethyl)p...)
Affinity DataIC50: 191nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/16/2025
Entry Details
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