BDBM739765 (S)-1-(3-(7-acetyl-4-amino-3-((2-methyl-2H-indazol-6-yl)alkynyl)-1H-pyrazolo[4,3-c]pyridin-1-yl)pyrrolidine-1-methyl)prop-2-en-1-one::US20250152564, Example 82

SMILES C=CC(=O)N1CC[C@H](n2nc(C#Cc3ccc4cn(C)nc4c3)c3c(N)ncc(C(C)=O)c32)C1

InChI Key InChIKey=FVBNNGBLKUMCEF-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 739765   

TargetFibroblast growth factor receptor 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM739765((S)-1-(3-(7-acetyl-4-amino-3-((2-methyl-2H-indazol...)
Affinity DataIC50: 1.40nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/15/2025
Entry Details
Go to US Patent

TargetFibroblast growth factor receptor 2(Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM739765((S)-1-(3-(7-acetyl-4-amino-3-((2-methyl-2H-indazol...)
Affinity DataIC50: 0.300nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/15/2025
Entry Details
Go to US Patent

TargetFibroblast growth factor receptor 3(Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM739765((S)-1-(3-(7-acetyl-4-amino-3-((2-methyl-2H-indazol...)
Affinity DataIC50: 0.5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/15/2025
Entry Details
Go to US Patent

TargetFibroblast growth factor receptor 2 [V564F](Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM739765((S)-1-(3-(7-acetyl-4-amino-3-((2-methyl-2H-indazol...)
Affinity DataIC50: 0.300nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/15/2025
Entry Details
Go to US Patent