BDBM739746 (S)-1-(3-(4-amino-3-((1-cyclopropyl-1H-benzo[d]imidazol-5-yl)ethynyl)-7-propionyl-1H-pyrazolo[4,3-c]pyridin-1-yl)pyrrolidin-1-yl)prop-2-en-1-one::US20250152564, Example 39

SMILES C=CC(=O)N1CC[C@H](n2nc(C#Cc3ccc4c(c3)ncn4C3CC3)c3c(N)ncc(C(=O)CC)c32)C1

InChI Key InChIKey=PQBDYJCATQLIFW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 739746   

TargetFibroblast growth factor receptor 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM739746((S)-1-(3-(4-amino-3-((1-cyclopropyl-1H-benzo[d]imi...)
Affinity DataIC50: 6.10nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/15/2025
Entry Details
Go to US Patent

TargetFibroblast growth factor receptor 2(Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM739746((S)-1-(3-(4-amino-3-((1-cyclopropyl-1H-benzo[d]imi...)
Affinity DataIC50: 1.70nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/15/2025
Entry Details
Go to US Patent

TargetFibroblast growth factor receptor 2 [V564F](Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM739746((S)-1-(3-(4-amino-3-((1-cyclopropyl-1H-benzo[d]imi...)
Affinity DataIC50: 0.600nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/15/2025
Entry Details
Go to US Patent