BDBM739742 (S)-1-(3-(7-acetyl-4-amino-3-((4,6-difluoro-1-methyl-1H-benzo[d]imidazol-5-yl)ethynyl)-1H-pyrazolo[4,3-c]pyridin-1-yl)pyrrolidin-1-yl)prop-2-en-1-one::US20250152564, Example 31

SMILES C=CC(=O)N1CC[C@H](n2nc(C#Cc3c(F)cc4c(ncn4C)c3F)c3c(N)ncc(C(C)=O)c32)C1

InChI Key InChIKey=OYJDTEBZSGLLNC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 739742   

TargetFibroblast growth factor receptor 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM739742((S)-1-(3-(7-acetyl-4-amino-3-((4,6-difluoro-1-meth...)
Affinity DataIC50: 3.5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/15/2025
Entry Details
Go to US Patent

TargetFibroblast growth factor receptor 2(Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM739742((S)-1-(3-(7-acetyl-4-amino-3-((4,6-difluoro-1-meth...)
Affinity DataIC50: 1.20nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/15/2025
Entry Details
Go to US Patent

TargetFibroblast growth factor receptor 2 [V564F](Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM739742((S)-1-(3-(7-acetyl-4-amino-3-((4,6-difluoro-1-meth...)
Affinity DataIC50: 0.800nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/15/2025
Entry Details
Go to US Patent