BDBM739740 (S)-1-(3-(4-amino-3-((6-fluoro-1-(methyl-d3)-1Hbenzo[d]imidazol-5-yl)ethynyl)-7-(thiazol-2-yl)-1Hpyrazolo[4,3-c]pyridin-1-yl)pyrrolidin-1-yl)prop-2-en-1-one::US20250152564, Example 25

SMILES [2H]C([2H])([2H])n6cnc5cc(C#Cc3nn([C@H]1CCN(C(=O)C=C)C1)c4c(c2nccs2)cnc(N)c34)c(F)cc56

InChI Key InChIKey=QKQUURVQHYEPRX-BMSJAHLVSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 739740   

TargetFibroblast growth factor receptor 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM739740((S)-1-(3-(4-amino-3-((6-fluoro-1-(methyl-d3)-1Hben...)
Affinity DataIC50: 5.70nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/15/2025
Entry Details
Go to US Patent

TargetFibroblast growth factor receptor 2(Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM739740((S)-1-(3-(4-amino-3-((6-fluoro-1-(methyl-d3)-1Hben...)
Affinity DataIC50: 1.5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/15/2025
Entry Details
Go to US Patent

TargetFibroblast growth factor receptor 2 [V564F](Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM739740((S)-1-(3-(4-amino-3-((6-fluoro-1-(methyl-d3)-1Hben...)
Affinity DataIC50: 0.600nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/15/2025
Entry Details
Go to US Patent