BDBM737731 (2R,3R,4S,5R,6R)-N-(3-chloro-5-cyanophenyl)-4-(4-(2,3-difluoro-4-methylphenyl)-1H-1,2,3-triazol-1-yl)-5-hydroxy-N-((1S,2S)-2-hydroxycyclohexyl)-6-(hydroxymethyl)-3-(2-morpholino-2-oxoethoxy)tetrahydro-2H-pyran-2-carboxamide::US12291519, Example 173

SMILES Cc1ccc(-c2cn([C@H]3[C@@H](O)[C@@H](CO)O[C@@H](C(=O)N(c4cc(Cl)cc(C#N)c4)[C@H]4CCCC[C@@H]4O)[C@@H]3OCC(=O)N3CCOCC3)nn2)c(F)c1F

InChI Key InChIKey=GGJAXDICRUQESB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 737731   

TargetGalectin-3(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM737731((2R,3R,4S,5R,6R)-N-(3-chloro-5-cyanophenyl)-4-(4-(...)
Ligand Info
In Depth
Date in BDB:
9/5/2025
Entry Details
Go to US Patent

TargetGalectin-1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM737731((2R,3R,4S,5R,6R)-N-(3-chloro-5-cyanophenyl)-4-(4-(...)
Affinity DataIC50: 509nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/5/2025
Entry Details
Go to US Patent