BDBM737663 (2R,3R,4S,5R,6R)-N-(3-chloro-5-methoxyphenyl)-5-hydroxy-N-((1S,2S)-2-hydroxycyclohexyl)-6-(hydroxymethyl)-3-methoxy-4-(4-(3,4,5-trifluorophenyl)-1H-1,2,3-triazol-1-yl)tetrahydro-2H-pyran-2-carboxamide::US12291519, Example 104

SMILES COc1cc(Cl)cc(N(C(=O)[C@@H]2O[C@H](CO)[C@H](O)[C@H](n3cc(-c4cc(F)c(F)c(F)c4)nn3)[C@H]2OC)[C@H]2CCCC[C@@H]2O)c1

InChI Key InChIKey=DSEOMQSTCAJEDC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 737663   

TargetGalectin-3(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM737663((2R,3R,4S,5R,6R)-N-(3-chloro-5-methoxyphenyl)-5-hy...)
Affinity DataIC50: 19nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/5/2025
Entry Details
Go to US Patent

TargetGalectin-1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM737663((2R,3R,4S,5R,6R)-N-(3-chloro-5-methoxyphenyl)-5-hy...)
Affinity DataIC50: 1.19E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/5/2025
Entry Details
Go to US Patent