BDBM737509 Synthesis of 1-(2-((3R,5S,8S,10S,13S,14S,17S)-3-hydroxy-3,10,13-trimethyl-2,3,4,5,6,7,8,10,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl)-1H-pyrazole-4-carbonitrile (A7) & 1-(2-((3R,5S,8S,10S,13S,14S,17R)-3-hydroxy-3,10,13-trimethyl-2,3,4,5,6,7,8,10,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl)-1H-pyrazole-4-carbonitrile (A8)::US20250136638, Example 3

SMILES C[C@@]1(O)CC[C@]2(C)C3=CC[C@]4(C)[C@H](C(=O)Cn5cc(C#N)cn5)CC[C@H]4[C@@H]3CC[C@H]2C1

InChI Key InChIKey=XRHVMZHKGNRLDB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 737509   

TargetGamma-aminobutyric acid receptor subunit alpha-1(Rat)
Sage Therapeutics

US Patent
LigandPNGBDBM737509(Synthesis of 1-(2-((3R,5S,8S,10S,13S,14S,17S)-3-hy...)
Affinity DataIC50: 5.50E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
Go to US Patent