BDBM734434 US20250129067, Compound Anlotinib

SMILES COc1cc2c(Oc3ccc4[nH]c(C)cc4c3F)ccnc2cc1OCC1(N)CC1

InChI Key InChIKey=KSMZEXLVHXZPEF-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 734434   

TargetPlatelet-derived growth factor receptor alpha(Human)
Progentos Therapeutics

US Patent
LigandPNGBDBM734434(US20250129067, Compound Anlotinib)
Affinity DataIC50: 1.36E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Go to US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Institute of Respiratory Health

Curated by ChEMBL
LigandPNGBDBM734434(US20250129067, Compound Anlotinib)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Institute of Respiratory Health

Curated by ChEMBL
LigandPNGBDBM734434(US20250129067, Compound Anlotinib)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Institute of Respiratory Health

Curated by ChEMBL
LigandPNGBDBM734434(US20250129067, Compound Anlotinib)
Affinity DataIC50: 0.200nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM734434(US20250129067, Compound Anlotinib)
Affinity DataIC50: 115nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed