BDBM7335 5-(4-aminobutoxy)-14-bromo-8,18-diazatetracyclo[9.7.0.0^{2,7}.0^{12,17}]octadeca-1(11),2,4,6,12(17),13,15-heptaen-9-one hydrochloride::NSC 716977::Paullone Analogue 70

SMILES NCCCCOc1ccc2-c3[nH]c4ccc(Br)cc4c3CC(=O)Nc2c1

InChI Key InChIKey=MAQBOTRSBYDGOL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 7335   

TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Spiny starfish)
Universitat Hamburg

LigandPNGBDBM7335(5-(4-aminobutoxy)-14-bromo-8,18-diazatetracyclo[9....)
Affinity DataIC50: 700nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2006
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5 activator 1 [99-307](Human)
Universitat Hamburg

LigandPNGBDBM7335(5-(4-aminobutoxy)-14-bromo-8,18-diazatetracyclo[9....)
Affinity DataIC50: 4.20E+5nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Rat)
Universitat Hamburg

LigandPNGBDBM7335(5-(4-aminobutoxy)-14-bromo-8,18-diazatetracyclo[9....)
Affinity DataIC50: 30nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2006
Entry Details Article
PubMed