BDBM733112 US20250115590, Compound PC-50

SMILES Cc1cc(COc2ccc(Sc3ccncc3C3NC(=O)NC3=O)c(F)c2)ccn1

InChI Key InChIKey=HKKVAUZCGNRBNA-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 733112   

TargetMacrophage metalloelastase(Human)
Foresee Pharmaceuticals USA

US Patent
LigandPNGBDBM733112(US20250115590, Compound PC-50)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Go to US Patent

TargetMacrophage metalloelastase(Human)
Foresee Pharmaceuticals USA

US Patent
LigandPNGBDBM733112(US20250115590, Compound PC-50)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Go to US Patent

TargetInterstitial collagenase(Human)
Foresee Pharmaceuticals USA

US Patent
LigandPNGBDBM733112(US20250115590, Compound PC-50)
Affinity DataIC50: 5.00E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Go to US Patent

Target72 kDa type IV collagenase(Human)
Foresee Pharmaceuticals USA

US Patent
LigandPNGBDBM733112(US20250115590, Compound PC-50)
Affinity DataIC50: 550nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Go to US Patent

TargetStromelysin-1(Human)
Foresee Pharmaceuticals USA

US Patent
LigandPNGBDBM733112(US20250115590, Compound PC-50)
Affinity DataIC50: 550nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Go to US Patent

TargetMatrilysin(Human)
Foresee Pharmaceuticals USA

US Patent
LigandPNGBDBM733112(US20250115590, Compound PC-50)
Affinity DataIC50: 5.00E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Go to US Patent

TargetNeutrophil collagenase(Human)
Foresee Pharmaceuticals USA

US Patent
LigandPNGBDBM733112(US20250115590, Compound PC-50)
Affinity DataIC50: 550nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Go to US Patent

TargetMatrix metalloproteinase-9(Human)
Foresee Pharmaceuticals USA

US Patent
LigandPNGBDBM733112(US20250115590, Compound PC-50)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Go to US Patent

TargetStromelysin-2(Human)
Foresee Pharmaceuticals USA

US Patent
LigandPNGBDBM733112(US20250115590, Compound PC-50)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Go to US Patent

TargetCollagenase 3(Human)
Foresee Pharmaceuticals USA

US Patent
LigandPNGBDBM733112(US20250115590, Compound PC-50)
Affinity DataIC50: 550nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Go to US Patent

TargetMatrix metalloproteinase-14(Human)
Foresee Pharmaceuticals USA

US Patent
LigandPNGBDBM733112(US20250115590, Compound PC-50)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Go to US Patent